Monogenic Causes Identified in 23.68% of Children with Steroid Resistant Nephrotic Syndrome: A Single-Centre Study

• Main Authors: Luyan Zhang (Author), Fei Zhao (Author), Guixia Ding (Author), Ying Chen (Author), Sanlong Zhao (Author), Qiuxia Chen (Author), Yugen Sha (Author), Ruochen Che (Author), Songming Huang (Author), Bixia Zheng (Author), Aihua Zhang (Author)
• Formato: Livro
• Publicado em: Karger Publishers, 2023-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Introduction: Steroid resistant nephrotic syndrome (SRNS) is the second most common cause of end-stage kidney disease in children, mostly associated with focal segmental glomerulosclerosis (FSGS). Advances in genomic science have enabled the identification of causative variants in 20 - 30% of SRNS p...