Synthesis of some quinazolinones inspired from the natural alkaloid L-norephedrine as EGFR inhibitors and radiosensitizers

• Main Authors: Mostafa M. Ghorab (Author), Maged S. Abdel-Kader (Author), Ali S. Alqahtani (Author), Aiten M. Soliman (Author)
• 格式: 圖書
• 出版: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

A set of quinazolinones synthesized by the aid of L-norephedrine was assembled to generate novel analogues as potential anticancer and radiosensitizing agents. The new compounds were evaluated for their cytotoxic activity against MDA-MB-231, MCF-7, HepG-2, HCT-116 cancer cell lines and EGFR inhibito...