Proinflammatory Responses of Heme in Alveolar Macrophages: Repercussion in Lung Hemorrhagic Episodes

• Hoofdauteurs: Rafael L. Simões (Auteur), Maria Augusta Arruda (Auteur), Cláudio Canetti (Auteur), Carlos H. Serezani (Auteur), Iolanda M. Fierro (Auteur), Christina Barja-Fidalgo (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2013-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Clinical and experimental observations have supported the notion that free heme released during hemorrhagic and hemolytic episodes may have a major role in lung inflammation. With alveolar macrophages (AM) being the main line of defense in lung environments, the influence of free heme on AM activity...