Opioid receptor desensitization: mechanisms and its link to tolerance

Opioid receptors are part of the class A of G-protein coupled receptors and the target of the opiates, the most powerful analgesic molecules used in clinic. During a protracted use, a tolerance to analgesic effect develops resulting in a reduction of the effectiveness. So understanding mechanisms of...

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Bibliographic Details
Main Authors: Stéphane eAllouche (Author), Florence eNoble (Author), Nicolas eMarie (Author)
Format: Book
Published: Frontiers Media S.A., 2014-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available