Clinical pharmacokinetics of capecitabine and its metabolites in colorectal cancer patients

• Main Authors: Saeed Alqahtani (Author), Rawan Alzaidi (Author), Abdullah Alsultan (Author), Abdulaziz Asiri (Author), Yousif Asiri (Author), Khalid Alsaleh (Author)
• Format: Book
• Published: Elsevier, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Capecitabine is one of the fluoropyrimidine anticancer agents which is extensively used in the management of colorectal cancer. We have noticed a discrepancy between the doses we are using in our patients and the recommended dosing regimen. Thus, this study aims to assess the pharmacokin...