Topical Delivery of Cell-Penetrating Peptide-Modified Human Growth Hormone for Enhanced Wound Healing

• Main Authors: Tru Van Nguyen (Author), Kyung-Hwa Lee (Author), Yongzhuo Huang (Author), Meong Cheol Shin (Author), Yoon Shin Park (Author), Hangun Kim (Author), Cheol Moon (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein drugs have been emerging as a class of promising therapeutics. However, their topical application has been limited by their high molecular weight and poor permeability to the cell membrane. In this study, we aimed to enhance human growth hormone (hGH) permeability for topical application by...