Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System of Raloxifene with Improved Solubility and Oral Bioavailability

• Автори: Muhammad Mohsin Ansari (Автор), Dang-Khoa Vo (Автор), Ho-Ik Choi (Автор), Jeong-Su Ryu (Автор), Yumi Bae (Автор), Nadeem Irfan Bukhari (Автор), Alam Zeb (Автор), Jin-Ki Kim (Автор), Han-Joo Maeng (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2023-08-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Poor aqueous solubility and dissolution limit the oral bioavailability of Biopharmaceutics Classification System (BCS) class II drugs. In this study, we aimed to improve the aqueous solubility and oral bioavailability of raloxifene hydrochloride (RLX), a BCS class II drug, using a self-microemulsify...