Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System of Raloxifene with Improved Solubility and Oral Bioavailability

• Main Authors: Muhammad Mohsin Ansari (Author), Dang-Khoa Vo (Author), Ho-Ik Choi (Author), Jeong-Su Ryu (Author), Yumi Bae (Author), Nadeem Irfan Bukhari (Author), Alam Zeb (Author), Jin-Ki Kim (Author), Han-Joo Maeng (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Poor aqueous solubility and dissolution limit the oral bioavailability of Biopharmaceutics Classification System (BCS) class II drugs. In this study, we aimed to improve the aqueous solubility and oral bioavailability of raloxifene hydrochloride (RLX), a BCS class II drug, using a self-microemulsify...