Rapid molecular imaging of active thrombi in vivo using aptamer-antidote probes

• Main Authors: Bethany Powell Gray (Author), Linsley Kelly (Author), Kady-Ann (Author), Juliana M. Layzer (Author), Rachel E. Rempel (Author), Shahid M. Nimjee (Author), Brian C. Cooley (Author), Alice F. Tarantal (Author), Bruce A. Sullenger (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pathological blood clotting, or thrombosis, limits vital blood flow to organs; such deprivation can lead to catastrophic events including myocardial infarction, pulmonary embolism, and ischemic stroke. Prompt restoration of blood flow greatly improves outcomes. We explored whether aptamers could ser...