A Novel Opener of Large-Conductance Ca2+-Activated K+ (BK) Channel Reduces Ischemic Injury in Rat Cardiac Myocytes by Activating Mitochondrial KCa Channel

• Những tác giả chính: Kazuho Sakamoto (Tác giả), Susumu Ohya (Tác giả), Katsuhiko Muraki (Tác giả), Yuji Imaizumi (Tác giả)
• Định dạng: Sách
• Được phát hành: Elsevier, 2008-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

It has been suggested that a new type of large-conductance Ca2+-activated K+ (BK) channel is distributed in the inner mitochondrial membrane (mitoKCa channel) and that its opening may attenuate ischemic cardiac injury. We examined effects of 12,14-dichlorodehydroabietic acid (diCl-DHAA), a novel BK-...