GDNF family receptor alpha‐like antagonist antibody alleviates chemotherapy‐induced cachexia in melanoma‐bearing mice

• Main Authors: Beom Yong Lee (Author), Jongwon Jeong (Author), Inseong Jung (Author), Hanchae Cho (Author), Dokyung Jung (Author), Jiwon Shin (Author), Jun‐kook Park (Author), Eunju Park (Author), Soojeong Noh (Author), Sanghee Shin (Author), Sungmin Kang (Author), Jong‐Ik Heo (Author), Moon‐Chang Baek (Author), Kyungmoo Yea (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Patients with cancer undergoing chemotherapy experience cachexia with anorexia, body weight loss, and the depletion of skeletal muscles and adipose tissues. Effective treatment strategies for chemotherapy‐induced cachexia are scarce. The growth differentiation factor 15 (GDF15)/G...