COX-2 Gene Promoter Polymorphism and Coronary Artery Disease in Middle-Aged Men: The Helsinki Sudden Death Study

• Hoofdauteurs: Kati H. Huuskonen (Auteur), Tarja A. Kunnas (Auteur), Minna M. Tanner (Auteur), Jussi Mikkelsson (Auteur), Erkki Ilveskoski (Auteur), Pekka J. Karhunen (Auteur), Seppo T. Nikkari (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2008-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Cyclooxygenase (COX) catalyzes formation of prostaglandins that contribute to the inflammation in atherosclerosis. Our objective was to study whether the functional C variant of the −765G→C polymorphism in the human COX-2 gene associates with the severity of coronary atherosclerosis measured at the...