Pathologic Findings of Chronic PML-IRIS in a Patient with Prolonged PML Survival Following Natalizumab Treatment

• Main Authors: Mai Himedan MD (Author), Sandra Camelo-Piragua MD (Author), Elizabeth A. Mills PhD (Author), Avneesh Gupta MD (Author), Rany Aburashed DO (Author), Yang Mao-Draayer MD, PhD (Author)
• Format: Book
• Published: SAGE Publishing, 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Immune reconstitution inflammatory syndrome (IRIS) is a common complication during treatment for natalizumab-associated progressive multifocal leukoencephalopathy (PML). Although severe IRIS can result in acute worsening of disability and is associated with poor prognosis, effective immune reconstit...