Myeloperoxidase Promoter Polymorphism −463G Is Associated With More Severe Clinical Expression of Cystic Fibrosis Pulmonary Disease

• Váldodahkkit: Wanda F. Reynolds (Dahkki), Isabelle Sermet-Gaudelus (Dahkki), Valérie Gausson (Dahkki), Marie-Noëlle Feuillet (Dahkki), Jean-Paul Bonnefont (Dahkki), Gérard Lenoir (Dahkki), Béatrice Descamps-Latscha (Dahkki), Véronique Witko-Sarsat (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Hindawi Limited, 2006-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The severity of cystic fibrosis (CF) pulmonary disease is not directly related to CFTR genotype but depends upon several parameters, including neutrophil-dominated inflammation. Identification of agents modulating inflammation constitutes a relevant goal. Myeloperoxidase (MPO) is involved in both mi...