Myeloperoxidase Promoter Polymorphism −463G Is Associated With More Severe Clinical Expression of Cystic Fibrosis Pulmonary Disease

• मुख्य लेखकों: Wanda F. Reynolds (लेखक), Isabelle Sermet-Gaudelus (लेखक), Valérie Gausson (लेखक), Marie-Noëlle Feuillet (लेखक), Jean-Paul Bonnefont (लेखक), Gérard Lenoir (लेखक), Béatrice Descamps-Latscha (लेखक), Véronique Witko-Sarsat (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2006-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The severity of cystic fibrosis (CF) pulmonary disease is not directly related to CFTR genotype but depends upon several parameters, including neutrophil-dominated inflammation. Identification of agents modulating inflammation constitutes a relevant goal. Myeloperoxidase (MPO) is involved in both mi...