Anti-Inflammatory Effect of Atorvastatin and Rosuvastatin on Monosodium Urate-Induced Inflammation through IL-37/Smad3-Complex Activation in an In Vitro Study Using THP-1 Macrophages

• Auteurs principaux: Seong-Kyu Kim (Auteur), Jung-Yoon Choe (Auteur), Ji-Won Kim (Auteur), Ki-Yeun Park (Auteur), Boyoung Kim (Auteur)
• Format: Livre
• Publié: MDPI AG, 2024-07-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

<b>Objective</b>: The pleiotropic effect of hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) is responsible for potent defense against inflammatory response. This study evaluated the inhibitory effects of HMG-CoA reductase inhibitors on the monosodium urate (M...