Impact of type 2 diabetes on in vivo activities and protein expressions of cytochrome P450 in patients with obesity

• Main Authors: Kine Eide Kvitne (Author), Anders Åsberg (Author), Line K. Johnson (Author), Christine Wegler (Author), Jens K. Hertel (Author), Per Artursson (Author), Cecilia Karlsson (Author), Shalini Andersson (Author), Rune Sandbu (Author), Eva Skovlund (Author), Hege Christensen (Author), Rasmus Jansson‐Löfmark (Author), Jøran Hjelmesæth (Author), Ida Robertsen (Author)
• Format: Book
• Published: Wiley, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Previous studies have not accounted for the close link between type 2 diabetes mellitus (T2DM) and obesity when investigating the impact of T2DM on cytochrome P450 (CYP) activities. The aim was to investigate the effect of T2DM on in vivo activities and protein expressions of CYP2C19, CYP3A...