Mitogen-Activated Protein Kinase Inhibitors and T-Cell-Dependent Immunotherapy in Cancer

• Main Authors: Sandeep Kumar (Author), Daniel R. Principe (Author), Sunil Kumar Singh (Author), Navin Viswakarma (Author), Gautam Sondarva (Author), Basabi Rana (Author), Ajay Rana (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitogen-activated protein kinase (MAPK) signaling networks serve to regulate a wide range of physiologic and cancer-associated cell processes. For instance, a variety of oncogenic mutations often lead to hyperactivation of MAPK signaling, thereby enhancing tumor cell proliferation and disease progre...