Mitogen-Activated Protein Kinase Inhibitors and T-Cell-Dependent Immunotherapy in Cancer

• Glavni autori: Sandeep Kumar (Autor), Daniel R. Principe (Autor), Sunil Kumar Singh (Autor), Navin Viswakarma (Autor), Gautam Sondarva (Autor), Basabi Rana (Autor), Ajay Rana (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2020-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Mitogen-activated protein kinase (MAPK) signaling networks serve to regulate a wide range of physiologic and cancer-associated cell processes. For instance, a variety of oncogenic mutations often lead to hyperactivation of MAPK signaling, thereby enhancing tumor cell proliferation and disease progre...