Celastrol Attenuates Lipid Accumulation and Stemness of Clear Cell Renal Cell Carcinoma via CAV-1/LOX-1 Pathway

• Asıl Yazarlar: Chan-Juan Zhang (Yazar), Neng Zhu (Yazar), Yu-Xiang Wang (Yazar), Le-Ping Liu (Yazar), Tan-Jun Zhao (Yazar), Hong-Tao Wu (Yazar), Duan-Fang Liao (Yazar), Li Qin (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Clear cell renal cell carcinoma (ccRCC) is characterized by abnormal lipid accumulation. Celastrol is a pentacyclic triterpene extracted from Tripterygium wilfordii Hook F with anti-cancer activity. In the present study, the anticancer effects of celastrol on ccRCC and the underlying mechanisms were...