Pharmacological Modulation of Blood-Brain Barrier Permeability by Kinin Analogs in Normal and Pathologic Conditions

• المؤلفون الرئيسيون: Dina Sikpa (مؤلف), Lisa Whittingstall (مؤلف), Martin Savard (مؤلف), Réjean Lebel (مؤلف), Jérôme Côté (مؤلف), Stephen McManus (مؤلف), Sylvain Chemtob (مؤلف), David Fortin (مؤلف), Martin Lepage (مؤلف), Fernand Gobeil (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2020-09-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The blood-brain barrier (BBB) is a major obstacle to the development of effective diagnostics and therapeutics for brain cancers and other central nervous system diseases. Peptide agonist analogs of kinin B1 and B2 receptors, acting as BBB permeabilizers, have been utilized to overcome this barrier....