Cutaneous Squamous Cell Carcinoma Developing from Recessive Dystrophic Epidermolysis Bullosa: A Case Report and an Immunohistochemical Study

• Main Authors: Akira Tsukada (Author), Taku Fujimura (Author), Sadanori Furudate (Author), Yumi Kambayashi (Author), Yukikazu Numata (Author), Takahiro Haga (Author), Akira Hashimoto (Author), Setsuya Aiba (Author)
• Format: Book
• Published: Karger Publishers, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We describe a 49-year-old Japanese woman with cutaneous squamous cell carcinoma (SCC) developing from recessive dystrophic epidermolysis bullosa (RDEB). Interestingly, immunohistochemical staining revealed dense infiltration of CD163+ M2 macrophages and numerous Foxp3+ regulatory T cells (Tregs) aro...