Effect of Phase-Change Nanodroplets and Ultrasound on Blood-Brain Barrier Permeability In Vitro

• Main Authors: Stavros Vlatakis (Author), Weiqi Zhang (Author), Sarah Thomas (Author), Paul Cressey (Author), Alexandru Corneliu Moldovan (Author), Hilde Metzger (Author), Paul Prentice (Author), Sandy Cochran (Author), Maya Thanou (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Phase-change nanodroplets (PCND;NDs) are emulsions with a perfluorocarbon (PFC) core that undergo acoustic vaporisation as a response to ultrasound (US). Nanodroplets change to microbubbles and cavitate while under the effect of US. This cavitation can apply forces on cell connections in biological...