Bromodomain and Extraterminal Proteins as Novel Epigenetic Targets for Renal Diseases

• Autors principals: Jose Luis Morgado-Pascual (Autor), Sandra Rayego-Mateos (Autor), Lucia Tejedor (Autor), Beatriz Suarez-Alvarez (Autor), Marta Ruiz-Ortega (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2019-11-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Epigenetic mechanisms, especially DNA methylation and histone modifications, are dynamic processes that regulate the gene expression transcriptional program in normal and diseased states. The bromodomain and extraterminal (BET) protein family (BRD2, BRD3, BRD4, and BRDT) are epigenetic readers that,...