Ultra-sensitive bioanalysis of the therapeutic peptide exenatide for accurate pharmacokinetic analyses at effective plasma concentrations utilizing UPLC-MS/MS
Exenatide is the first approved glucagon-like peptide 1 receptor agonist subcutaneously or intramuscularly injected for the treatment of type 2 diabetes mellitus. Typical therapeutic plasma concentrations are in the low pg/mL range, therefore requiring ultra-sensitive quantification. To enable the a...
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Main Authors: | Max Sauter (Author), Philipp Uhl (Author), Jürgen Burhenne (Author), Walter E. Haefeli (Author) |
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Format: | Book |
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Elsevier,
2020-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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