Increased testicular insulin-like growth factor 1 is associated with gonadal activation by recombinant growth hormone in immature rats

• Główni autorzy: Yang Xu (Autor), Chang Yong Han (Autor), Mi Jung Park (Autor), Myung Chan Gye (Autor)
• Format: Książka
• Wydane: BMC, 2022-04-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background In children, recombinant human growth hormone (rhGH) therapy for treatment of short stature has raised concerns of the early onset of puberty. Puberty is initiated by the activation of the hypothalamus-pituitary-gonad axis. Insulin-like growth factor-1 (IGF1) has been known to me...