Adjusting Heterodimeric Coiled-Coils (K/E Zipper) to Connect Autophagy-Inducing Peptide with Cell-Penetrating Peptide

• Main Authors: Yoshiyuki Hakata (Author), Kazuma Yamashita (Author), Sonoko Hashimoto (Author), Takashi Ohtsuki (Author), Masaaki Miyazawa (Author), Mizuki Kitamatsu (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A connection of a functional peptide with a cell-penetrating peptide (CPP) used a heterodimeric coiled-coil as a molecular zipper can improve the intracellular delivery and activity of the functional peptide. However, the chain length of the coiled coil required for functioning as the molecular zipp...