A Peptide Inhibitor of Peroxiredoxin 6 Phospholipase A₂ Activity Significantly Protects against Lung Injury in a Mouse Model of Ventilator Induced Lung Injury (VILI)

• Main Authors: Aron B. Fisher (Author), Chandra Dodia (Author), Shampa Chatterjee (Author)
• Format: Bog
• Udgivet: MDPI AG, 2021-06-01T00:00:00Z.
• Fag: article
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Ventilator induced lung injury (VILI) is a lung injury syndrome associated with mechanical ventilation, most frequently for treatment of Acute Lung Injury (ALI), and generally secondary to the use of greater than physiologic tidal volumes. To reproduce this syndrome experimentally, C57Bl/6 mice were...