Allergic Airway-Induced Hypersensitivity Is Attenuated by Bergapten in Murine Models of Inflammation

• Autors principals: Douglas B. Aidoo (Autor), David D. Obiri (Autor), Newman Osafo (Autor), Aaron O. Antwi (Autor), Leslie B. Essel (Autor), Babatunde M. Duduyemi (Autor), Martins Ekor (Autor)
• Format: Llibre
• Publicat: Hindawi Limited, 2019-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Bergapten (5-methoxypsoralen, 5-MOP) is a plant-derived furocoumarin with demonstrated anti-inflammatory action. The present study investigated its effects on allergic inflammation in two related pathways of mast cell degranulation. Compound 48/80 and lipopolysaccharide (LPS) were used to activate t...