Allergic Airway-Induced Hypersensitivity Is Attenuated by Bergapten in Murine Models of Inflammation

• Main Authors: Douglas B. Aidoo (Author), David D. Obiri (Author), Newman Osafo (Author), Aaron O. Antwi (Author), Leslie B. Essel (Author), Babatunde M. Duduyemi (Author), Martins Ekor (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bergapten (5-methoxypsoralen, 5-MOP) is a plant-derived furocoumarin with demonstrated anti-inflammatory action. The present study investigated its effects on allergic inflammation in two related pathways of mast cell degranulation. Compound 48/80 and lipopolysaccharide (LPS) were used to activate t...