Development of physiologically‐based pharmacokinetic models for standard of care and newer tuberculosis drugs

• Main Authors: Helen Humphries (Author), Lisa Almond (Author), Alexander Berg (Author), Iain Gardner (Author), Oliver Hatley (Author), Xian Pan (Author), Ben Small (Author), Mian Zhang (Author), Masoud Jamei (Author), Klaus Romero (Author)
• Format: Book
• Published: Wiley, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Tuberculosis (TB) remains a global health problem and there is an ongoing effort to develop more effective therapies and new combination regimes that can reduce duration of treatment. The purpose of this study was to demonstrate utility of a physiologically‐based pharmacokinetic modeling ap...