Comparison of clozapine doses and tolerability in patients with and without concurrent valproic acid

• Main Authors: Ranel Troy Santos, PharmD, BCPP (Author), Sandra Mullen, PharmD, BCPP (Author), Ericka L. Crouse, PharmD, BCPP, BCGP, FASHP, FASCP (Author), Katie S. Adams, PharmD, BCPP (Author)
• 格式: 圖書
• 出版: American Association of Psychiatric Pharmacists, 2023-01-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Introduction: Valproic acid (VPA) and its various formulations can be given in conjunction with clozapine for seizure prophylaxis or for augmentation in schizophrenia. There is conflicting literature on how VPA affects clozapine metabolism and the incidence of clozapine-related side effects. The pur...