Sirtuin modulators control reactive gliosis in an in vitro model of Alzheimer's disease

• Main Authors: Caterina eScuderi (Author), Claudia eStecca (Author), Maria Rosanna Bronzuoli (Author), Dante eRotili (Author), Sergio eValente (Author), Antonello eMai (Author), Luca eSteardo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2014-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Among neurodegenerative disorders, Alzheimer's disease (AD) represents the most common cause of dementia in the elderly. Several genetic and environmental factors have been identified, however aging represents the most important risk factor in the development of AD. To date, no effective treatm...