Antagonist targeting microRNA-155 protects against lithium-pilocarpine-induced status epilepticus in C57BL/6 mice by activating brain-derived neurotrophic factor

• Main Authors: Zhengxu eCai (Author), song eli (Author), sheng eli (Author), Fan eSong (Author), Zhen eZhang (Author), Guanhua eQi (Author), Tianbai eLi (Author), Juanjuan eQiu (Author), Jiajia eWan (Author), Hua eSui (Author), Huishu eGuo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epilepsy is a severe brain disorder affecting numerous patients. Recently, it is inferred that modulation of microRNA-155 (miR-155) could serve as a promising treatment of mesial temporal lobe epilepsy (MTLE). In the current study, the therapeutic potential of miR-155 antagonist against TLE was eval...