Synthesis and Design of Purpurin-18-Loaded Solid Lipid Nanoparticles for Improved Anticancer Efficiency of Photodynamic Therapy

• Main Authors: Sooho Yeo (Author), Hyeon Ho Song (Author), Min Je Kim (Author), Seokhyeon Hong (Author), Il Yoon (Author), Woo Kyoung Lee (Author)
• 格式: 圖書
• 出版: MDPI AG, 2022-05-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Purpurin-18 (P18) is one of the essential photosensitizers used in photodynamic therapy (PDT), but its hydrophobicity causes easy coalescence and poor bioavailability. This study aimed to synthesize P18 and design P18-loaded solid lipid nanoparticles (SLNs) to improve its bioavailability. The charac...