Splenic Stromal Cells from Aged Mice Produce Higher Levels of IL-6 Compared to Young Mice

• Main Authors: Jihyun Park (Author), Takuya Miyakawa (Author), Aya Shiokawa (Author), Haruyo Nakajima-Adachi (Author), Masaru Tanokura (Author), Satoshi Hachimura (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflamm-aging indicates the chronic inflammatory state resulting from increased secretion of proinflammatory cytokines and mediators such as IL-6 in the elderly. Our principle objective was to identify cell types that were affected with aging concerning IL-6 secretion in the murine model. We compare...