18-α-glycyrrhetinic acid alleviates oxidative damage in periodontal tissue by modulating the interaction of Cx43 and JNK/NF-κB pathways

• Main Authors: Niuben Cao (Author), Xiaomeng Liu (Author), Yubo Hou (Author), Yu Deng (Author), Yu Xin (Author), Xirui Xin (Author), Xinchen Xiang (Author), Xinchan Liu (Author), Weixian Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Periodontitis is a common chronic inflammatory disease in which oxidative stress is one of the key pathogenic factors. Connexin43 (Cx43) is the most critical and widely distributed connexin isoform. When the organism undergoes a severe and sustained stress response, Cx43-mediated gap junc...