Astrocyte Elevated Gene-1 Mediates Glycolysis and Tumorigenesis in Colorectal Carcinoma Cells via AMPK Signaling
To investigate the role of AEG-1 in glycolysis and tumorigenesis, we construct myc-AEG-1 expression vector and demonstrate a novel mechanism that AEG-1 may increase the activity of AMPK by Thr172 phosphorylation. The higher expression levels of AEG-1 in colorectal carcinoma cells were found but show...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2014-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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