Novel <it>APC </it>mutations in Czech and Slovak FAP families: clinical and genetic aspects

• Hoofdauteurs: Vesela Kamila (Auteur), Ilencikova Denisa (Auteur), Kotlas Jaroslav (Auteur), Zidkova Katerina (Auteur), Kebrdlova Vera (Auteur), Sulova Martina (Auteur), Stekrova Jitka (Auteur), Kohoutova Milada (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2007-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Germline mutations in the adenomatous polyposis gene (<it>APC</it>) result in familial adenomatous polyposis (FAP). FAP is an autosomal dominantly inherited disorder predisposing to colorectal cancer. Typical FAP is chara...