Development of a Stable Respiratory Syncytial Virus Pre-Fusion Protein Powder Suitable for a Core-Shell Implant with a Delayed Release in Mice: A Proof of Concept Study

• Main Authors: Max Beugeling (Author), Katie Amssoms (Author), Freek Cox (Author), Ben De Clerck (Author), Ellen Van Gulck (Author), Jeroen A. Verwoerd (Author), Guenter Kraus (Author), Dirk Roymans (Author), Lieven Baert (Author), Henderik W. Frijlink (Author), Wouter L. J. Hinrichs (Author)
• Format: Book
• Published: MDPI AG, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Currently, there is an increasing interest to apply pre-fusion (pre-F) protein of respiratory syncytial virus (RSV) as antigen for the development of a subunit vaccine. A pre-F-containing powder would increase the flexibility regarding the route of administration. For instance, a pre-F-containing po...