Identification of the potential mechanisms of Huzhang Tongfeng Granules against acute gouty arthritis through network pharmacology and in vivo analysis

• Main Authors: Mi Zhou (Author), Ying Zhang (Author), Zhan Zhang (Author), Xiaojie Ding (Author), Yue Luo (Author), Xiaoya Fei (Author), Jiankun Song (Author), Dan Yang (Author), Siting Chen (Author), Bin Li (Author), Le Kuai (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To identify the potential mechanism of Huzhang Tongfeng Granules (HTG) for the treatment of acute gouty arthritis (AGA). Methods: First of all, we used network pharmacology to build a network of components-targets of HTG. Secondly, the ClusterONE algorithm was applied to construct a modul...