Prevalence estimation of microsatellite instability in colorectal cancers using tissue microarray based methods - A tertiary care center experience

• Main Authors: Sonali Susmita Nayak (Author), Paromita Roy (Author), Neeraj Arora (Author), Indu Arun (Author), Manas Kumar Roy (Author), Sudeep Banerjee (Author), Indranil Mallick (Author), Mohandas K Mallath (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aim: Microsatellite instability (MSI) pathway is known to be implicated in carcinogenesis of 15% colorectal carcinomas (CRC), including 2%-3% of cases of Lynch syndrome, as per western literature. MSI status has important prognostic and therapeutic implications. The prevalence of MSI in Indian CRC p...