Plasma metabolomic and lipidomic alterations associated with anti-tuberculosis drug-induced liver injury

• Egile Nagusiak: Ming-Gui Wang (Egilea), Shou-Quan Wu (Egilea), Meng-Meng Zhang (Egilea), Jian-Qing He (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background: Anti-tuberculosis drug-induced liver injury (ATB-DILI) is an adverse reaction with a high incidence and the greatest impact on tuberculosis treatment. However, there is a lack of effective biomarkers for the early prediction of ATB-DILI. Herein, this study uses UPLC‒MS/MS to reveal the p...