Plasma metabolomic and lipidomic alterations associated with anti-tuberculosis drug-induced liver injury

• Autori principali: Ming-Gui Wang (Autore), Shou-Quan Wu (Autore), Meng-Meng Zhang (Autore), Jian-Qing He (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background: Anti-tuberculosis drug-induced liver injury (ATB-DILI) is an adverse reaction with a high incidence and the greatest impact on tuberculosis treatment. However, there is a lack of effective biomarkers for the early prediction of ATB-DILI. Herein, this study uses UPLC‒MS/MS to reveal the p...