Ca2 + release and buffering effects of synthetic hydroxyapatite following bacterial acid challenge

• Main Authors: Fabian Cieplik (Author), Christina M. Rupp (Author), Stefanie Hirsch (Author), Denise Muehler (Author), Joachim Enax (Author), Frederic Meyer (Author), Karl-Anton Hiller (Author), Wolfgang Buchalla (Author)
• Format: Book
• Published: BMC, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Synthetic particulate hydroxyapatite (HAP; Ca5(PO4)3(OH)) is used as ingredient in oral care products but its effects on cariogenic biofilms are not clear yet. The primary mode of action of HAP may be acting as a calcium phosphate reservoir when deposited in oral biofilms and rel...