Acute morphine activates satellite glial cells and up-regulates IL-1β in dorsal root ganglia in mice via matrix metalloprotease-9

• Главные авторы: Berta Temugin (Автор), Liu Tong (Автор), Liu Yen-Chin (Автор), Xu Zhen-Zhong (Автор), Ji Ru-Rong (Автор)
• Формат: ‌
• Опубликовано: SAGE Publishing, 2012-03-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Activation of spinal cord glial cells such as microglia and astrocytes has been shown to regulate chronic opioid-induced antinociceptive tolerance and hyperalgesia, due to spinal up-regulation of the proinflammatory cytokines such as...