Targeting the Microenvironment in MDS: The Final Frontier

• Main Authors: Patric Teodorescu (Author), Sergiu Pasca (Author), Delia Dima (Author), Ciprian Tomuleasa (Author), Gabriel Ghiaur (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Myelodysplastic syndromes (MDS) are a heterogeneous group of malignant disorders of hematopoietic stem and progenitor cells (HSPC), mainly characterized by ineffective hematopoiesis leading to peripheral cytopenias and progressive bone marrow failure. While clonal dominance is nearly universal at di...