Development and performance of the c4c national clinical trial networks for optimizing pediatric trial facilitation

• Prif Awduron: Eva Degraeuwe (Awdur), Tessa van der Geest (Awdur), Laura Persijn (Awdur), Lieve Nuytinck (Awdur), Ann Raes (Awdur), Mark Turner (Awdur), Ricardo M. Fernandes (Awdur), Johan Vande Walle (Awdur), Saskia N. de Wildt (Awdur), IMI2 project conect4children (c4c) (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

IntroductionThe high failure rate of industry-driven pediatric clinical trials leads to insufficient timely labeling of drugs in children and a lack of scientific evidence, resulting in the persistently high off-label drug use. National clinical trial networks can facilitate collaboration between si...