Generation of reactive oxygen species by hydroxypyridone compound/iron complexes
Objectives: Prooxidant properties of iron-binding hydroxypyridone compounds including deferiprone and mimosine were analyzed. Methods: Hydroxypyridone/iron-dependent production of reactive oxygen species was evidenced by the inactivation of aconitase, the most sensitive enzyme to oxidative stress in...
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Format: | Book |
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Taylor & Francis Group,
2020-01-01T00:00:00Z.
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A1234.567 |
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