Si-Miao-Yong-An Decoction Protects Against Cardiac Hypertrophy and Dysfunction by Inhibiting Platelet Aggregation and Activation

• Main Authors: Congping Su (Author), Qing Wang (Author), Huimin Zhang (Author), Wenchao Jiao (Author), Hui Luo (Author), Lin Li (Author), Xiangyang Chen (Author), Bin Liu (Author), Xue Yu (Author), Sen Li (Author), Wei Wang (Author), Shuzhen Guo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The aim of this study was to determine whether Si-Miao-Yong-An decoction (SMYAD) could ameliorate pressure overload-induced heart hypertrophy and its mechanisms.Methods: C57BL/6 mice were subjected to either sham or transverse aortic constriction (TAC) surgery to induce heart hypertrophy....