Formulation of the novel structure curcumin derivative-loaded solid lipid nanoparticles: synthesis, optimization, characterization and anti-tumor activity screening in vitro

• Main Authors: Ke Li (Author), Chao Pi (Author), Jie Wen (Author), Yingmeng He (Author), Jiyuan Yuan (Author), Hongping Shen (Author), Wenmei Zhao (Author), Mingtang Zeng (Author), Xinjie Song (Author), Robert J. Lee (Author), Yumeng Wei (Author), Ling Zhao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigated the effect of structural modification of Curcumin (CU) combined with the solid lipid nanoparticles (SLN) drug delivery system on anti-tumor activity in vitro. A new structure of Curcumin derivative (CU1) was successfully synthesized by modifying the phenolic hydroxyl group of...