Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia

• Автори: Hongguang Fan (Автор), Litao Li (Автор), Xiangjian Zhang (Автор), Ying Liu (Автор), Chenhui Yang (Автор), Yi Yang (Автор), Jing Yin (Автор)
• Формат: Книга
• Опубліковано: Hindawi Limited, 2009-01-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Inflammatory damage plays an important role in cerebral ischemic pathogenesis and may represent a target for treatment. Toll-like receptor-4 (TLR4), toll-like receptor-2 (TLR2), myeloid differentiation factor 88 (MyD88), and nuclear factor kappa-B (NF-κB) have been linked to inflammatory reactions....