Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia

Oxymatrine Downregulates TLR4, TLR2, MyD88, and NF-κB and Protects Rat Brains against Focal Ischemia

Inflammatory damage plays an important role in cerebral ischemic pathogenesis and may represent a target for treatment. Toll-like receptor-4 (TLR4), toll-like receptor-2 (TLR2), myeloid differentiation factor 88 (MyD88), and nuclear factor kappa-B (NF-κB) have been linked to inflammatory reactions....

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Main Authors: Hongguang Fan (Author), Litao Li (Author), Xiangjian Zhang (Author), Ying Liu (Author), Chenhui Yang (Author), Yi Yang (Author), Jing Yin (Author)
Format: Book
Published: Hindawi Limited, 2009-01-01T00:00:00Z.
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